Richard B. Silverman Curriculum Vitae

Contact Information

Address:
Department of Chemistry
Northwestern University
2145 Sheridan Road
Evanston, IL 60208-3113

Telephone (847) 491-5653
FAX: (847) 491-7713

Internet: Agman@chem.northwestern.edu
Web: https://www.silverman.northwestern.edu

Date of Birth: May 12, 1946; Philadelphia, PA; married, 3 children

2015-present Patrick G. Ryan/Aon Professor, Northwestern University
2004-2015 John Evans Professor of Chemistry, Northwestern University
2001-2004 Charles Deering McCormick Professor of Teaching Excellence, Northwestern University
1986-present Professor of Chemistry and Professor of Molecular Biosciences Northwestern University
1982-1986 Associate Professor of Chemistry, Northwestern University
1976-1982 Assistant Professor of Chemistry, Northwestern University

1974-1976 NIH Postdoctoral Fellow, Brandeis University, enzymology (Robert H. Abeles)
1971-1974 Harvard University, Ph.D. (continued) in organic chemistry (David H. Dolphin)
1969-1971 U.S. Army (Walter Reed Army Institute of Research)
1968-1969 Harvard University, Ph.D. in organic chemistry (interrupted by military service)
1964-1968 Pennsylvania State University, B.S. in chemistry (Roy A. Olofson)

2023 Elected Member, National Academy of Sciences
2021 Tetrahedron Prize for Creativity in Bioorganic and Medicinal Chemistry
2017 Creative Invention Award, American Chemical Society
2014 Elected Fellow, American Academy of Arts & Sciences
2014 Elected Fellow, National Academy of Inventors
2014 iCON Innovator Award of the iBIO Institute
2014 Northwestern Trustee Medal for Faculty Innovation and Entrepreneurship
2014 Medicinal Chemistry Prize of the Israel Chemical Society
2013 Fellow of the Royal Society of Chemistry (UK)
2013 Centenary Prize of the Royal Society of Chemistry
2013 Bristol-Myers Squibb-Edward E. Smissman Award of the ACS
2013 Sato Memorial International Award of the Pharmaceutical Society of Japan
2011 E. B. Hershberg Award for Important Discoveries in Medicinally Active Substances of the ACS
2011 Fellow of the American Chemistry Society
2009 Perkin Medal, Society of Chemical Industry
2009 Medicinal Chemistry Hall of Fame of the ACS

2005 Inventor of Lyrica^&Reg; (pregabalin), marketed worldwide by Pfizer for the treatment of fibromyalgia, neuropathic pain, epilepsy, and (in Europe) for generalized anxiety
2015 Inventor of CPP-115, successful completion of Phase 1 clinical trial; currently used, via an emergency use IND, for a child with infantile spasms
2016 Inventor of OV329, licensed to Ovid Therapeutics for movement disorders, currently in clinical trials
2020 Inventor of NU-9 (AKV9), licensed to Akava Therapeutics, a company I founded, for treatment of amyotrophic lateral sclerosis (ALS); IND approved by FDA

Publication & Patent Summary: 398 publications, 5 books, 130 issued patents (93 U.S. patents)

Silverman, R.B.; Holladay, M. W. The Organic Chemistry of Drug Design and Drug Action; 3^rd Edition; Elsevier/Academic Press: San Diego; 2014