Richard B. Silverman Curriculum Vitae

Richard B. SilvermanContact Information

Department of Chemistry
Northwestern University
2145 Sheridan Road
Evanston, IL 60208-3113

Telephone (847) 491-5653
FAX: (847) 491-7713


Date of Birth: May 12, 1946; Philadelphia, PA; married, 3 children

Positions Held

  • 2015-present Patrick G. Ryan/Aon Professor, Northwestern University
  • 2004-2015 John Evans Professor of Chemistry, Northwestern University
  • 2001-2004 Charles Deering McCormick Professor of Teaching Excellence, Northwestern University
  • 1986-present Professor of Chemistry and Professor of Molecular Biosciences Northwestern University
  • 1982-1986 Associate Professor of Chemistry, Northwestern University
  • 1976-1982 Assistant Professor of Chemistry, Northwestern University


  • 1974-1976 NIH Postdoctoral Fellow, Brandeis University, enzymology (Robert H. Abeles)
  • 1971-1974 Harvard University, Ph.D. (continued) in organic chemistry (David H. Dolphin)
  • 1969-1971 U.S. Army (Walter Reed Army Institute of Research)
  • 1968-1969 Harvard University, Ph.D. in organic chemistry (interrupted by military service)
  • 1964-1968 Pennsylvania State University, B.S. in chemistry (Roy A. Olofson)

Awards and Honors (since 2009)

  • 2023 Elected Member, National Academy of Sciences
  • 2021 Tetrahedron Prize for Creativity in Bioorganic and Medicinal Chemistry
  • 2017 Creative Invention Award, American Chemical Society
  • 2014 Elected Fellow, American Academy of Arts & Sciences
  • 2014 Elected Fellow, National Academy of Inventors
  • 2014 iCON Innovator Award of the iBIO Institute
  • 2014 Northwestern Trustee Medal for Faculty Innovation and Entrepreneurship
  • 2014 Medicinal Chemistry Prize of the Israel Chemical Society
  • 2013 Fellow of the Royal Society of Chemistry (UK)
  • 2013 Centenary Prize of the Royal Society of Chemistry
  • 2013 Bristol-Myers Squibb-Edward E. Smissman Award of the ACS
  • 2013 Sato Memorial International Award of the Pharmaceutical Society of Japan
  • 2011 E. B. Hershberg Award for Important Discoveries in Medicinally Active Substances of the ACS
  • 2011 Fellow of the American Chemistry Society
  • 2009 Perkin Medal, Society of Chemical Industry
  • 2009 Medicinal Chemistry Hall of Fame of the ACS

Pharmaceutical Inventions

  • 2005 Inventor of Lyrica&Reg; (pregabalin), marketed worldwide by Pfizer for the treatment of fibromyalgia, neuropathic pain, epilepsy, and (in Europe) for generalized anxiety
  • 2015 Inventor of CPP-115, successful completion of Phase 1 clinical trial; currently used, via an emergency use IND, for a child with infantile spasms
  • 2016 Inventor of OV329, licensed to Ovid Therapeutics for movement disorders, currently in clinical trials
  • 2020 Inventor of NU-9 (AKV9), licensed to Akava Therapeutics, a company I founded, for treatment of amyotrophic lateral sclerosis (ALS); IND approved by FDA

Publication & Patent Summary: 398 publications, 5 books, 130 issued patents (93 U.S. patents)

Medicinal Chemistry Textbook

Silverman, R.B.; Holladay, M. W. The Organic Chemistry of Drug Design and Drug Action; 3rd Edition; Elsevier/Academic Press: San Diego; 2014

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