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Department of Medicinal Chemistry and Molecular Pharmacology Personnel - G. Marc Loudon

G. Marc Loudon, Ph.D.
Gustav E. Cwalina Distinguished Professor of Medicinal Chemistry
Phone: 765-494-1462
Fax: 765-494-7880
E-mail: loudonm@purdue.edu
Personal webpage: http://people.pharmacy.purdue.edu/~loudonm/

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Picture of G. Marc Loudon

Education

B.S. in Chemistry (Magna cum laude) - 1964 Louisiana State University
Ph.D. in Physical-Organic Chemistry - 1968 University of California, Berkeley (with D. S. Noyce)
Postdoc. in Biochemistry - 1968-70 University of California, Berkeley (with D. E. Koshland, Jr.)

Research

My laboratory research interests are in mechanism-based drug design, organic reaction mechanisms in aqueous solution, enzyme mechanisms, and peptide chemistry. My last projects included the design, synthesis and evaluation of a family of aziridine-based inhibitors of the HIV protease, carboxy-terminal peptide degradation, and site-specific peptide cleavage reactions. Because of my activities in administration and teaching, I do not have a regular research group. However, I am available to serve on committees and to co-direct projects in other laboratories that are within my areas of expertise.

I am also studying (in collaboration with George Bodner in the Department of Chemistry) teaching and learning in organic chemistry. A current project involves comparison teaching of sophomore organic chemistry using cooperative learning and standard lecture approaches.

Lab Members:

Interests

My current active interests are in university administration, teaching, and the developing of instructional materials. I am the author of Organic Chemistry, 5th Edition, published by Roberts and Company, and am a co-author of both Study Guide and Instructor Supplement to accompany that text. I have, in collaboration with George Bodner in the Division of Chemical Education, been developing a group-study approach to teaching organic chemistry, which has been implemented in the last several years in my organic chemistry course at Purdue (which has between 200-300 students). I am currently interested in working on a revision of the chemistry curriculum for pre-pharmacy, pre-medical, pre-biology, and pre-veterinary students.

Service and Engagement

Associate Dean for Research and Graduate Programs for the College of Pharmacy, Nursing, and Health Sciences, 1988-2007.

Teaching

My principal teaching responsibilities are MCMP 204-205 (Organic Chemistry)

Representative Publications

Marc Loudon, Organic Chemistry, 5th Edition. Greenwood Village CO: Roberts and Company, 2008
 
Marc Loudon and Joseph G. Stowell, Study Guide and Solutions Manual to Accompany Organic Chemistry, 5th Edition. Greenwood Village CO: Roberts and Company, 2009
 
G. M. Loudon, Organic Chemistry, 4th Edition. New York: Oxford University Press (2002).
 
G. M. Loudon and Joseph G. Stowell, Study Guide and Solutions Manual to Accompany Organic Chemistry, 4th Edition. New York: Oxford University Press (2002).
 
G. M. Loudon and David M. Allen, Dynamic Organic Chemistry. (Animations to accompany Organic Chemistry, 4th Edition.) New York: Oxford University Press (2003).
 
V. L. Boyd, M. Bozzini, P. J. Guga, R. J. DeFranco, P.-M. Yuan, G. M. Loudon, and D. Nguyen, "Activation of the Carboxy Terminus of a Peptide for Carboxy-Terminal Sequencing," J. Org. Chem., 1995, 60, 2581-2587.
 
R. L. Geahlen, G. M. Loudon, L. A. Paige, and D. Lloyd, "A General Method for Preparation of Peptides Biotinylated at the Carboxy Terminus," Analytical Biochem. 1992, 202, 68-70.
 
G. M. Loudon, "Mechanistic Interpretation of pH-Rate Profiles," J. Chem. Educ. 1991, 68, 973-974.

Curriculum Vitae

Click here for a full CV for G. Marc Loudon. (an Adobe Acrobat file)

This record was last updated on Jun 6, 2013 at 11:40 AM
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